Flexing Your Early Cancer Detection Muscles
Strengthening Your Knowledge of Blood-Based Screening Tools
Clinical Practice Guidelines
US Preventive Services Task Force. Published Recommendations for Cancer.
A and B Recommendations
Clinician Resources
Prevent Cancer Foundation.
Multi-cancer early detection coverage and legislation.
Surveillance, Epidemiology, and End Results (SEER) *Explorer
An interactive website for SEER cancer statistics. Surveillance Research Program, National Cancer Institute, Division of Cancer Control and Population Sciences.
Galleri Test Website
Menlo Park, CA: Grail LLC.
Suggested Readings
Non-invasive early detection of cancer four years before conventional diagnosis using a blood test.
Chen X, et al. Nat Commun. 2020;11(1):3475.
Cell-free DNA analysis in current cancer clinical trials: a review.
Cisneros-Villanueva M, et al. Br J Cancer. 2022;126(3):391-400.
Projected reductions in absolute cancer–related deaths from diagnosing cancers before metastasis, 2006–2015.
Clarke CA, et al. Cancer Epidemiol Biomarkers Prev. 2020;29(5):895-902.
Modeled reductions in late-stage cancer with a multi-cancer early detection test.
Hubbell E, et al. Cancer Epidemiol Biomarkers Prev. 2021;30(3):460-468.
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set.
Klein EA, et al. Ann Oncol. 2021;32(9):1167-1177.
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA.
Liu MC, et al. Ann Oncol. 2020;31(6):745-759.
The PATHFINDER Study: assessment of the implementation of an investigational multi-cancer early detection test into clinical practice.
Nadauld LD, et al. Cancers (Basel). 2021;13(14):3501.
Updates on liquid biopsy: current trends and future perspectives for clinical application in solid tumors.
Pinzani P, et al. Clin Chem Lab Med. 2021;59(7):1181-1200.
Sensitivity, specificity, and predictive values: foundations, pliabilities, and pitfalls in research and practice.
Trevethan R. Front Public Health. 2017;5.
Strengthening Your Knowledge of Blood-Based Screening Tools
Relevant Resources
Overcoming Pain and Gastrointestinal Distress to Improve Patient Outcomes
Evidence-Based Strategies for Improved Patient Outcomes
Proactive Diagnosis and Targeted Management
Differential Diagnosis and Comprehensive Management Strategies
Optimizing Maintenance Therapy Across Healthcare Settings
Evolving Strategies for Diagnosis and Long-Term Management
Consensus and Controversies for Responsible Opioid Prescribing
Best Practices in Combination Therapy
Evolving Approaches to Insulin Based Therapy
Improving Outcomes for Patients with COPD
New Strategies for Insulin Replacement Therapy
Clinical Updates in LDL-C Management
Improving Comprehensive Patient Care
Identifying Patients and Tailoring Therapy
Collaborative Approaches to Guideline-Concordant Patient Care
New Strategies for Individualizing Long-term Care
A Focus on Patients With Opioid-Induced Constipation
Consensus and Controversies Across the Spectrum of Patient Presentations
Evolving Treatment Algorithms and Expert Perspectives on Biosimilars
Evolving Best Practices to Optimize Outcomes
The PCP’s Role in Timely Recognition and Referral
Differential Diagnosis, Multidisciplinary Management, and Patient Engagement
Key Issues Impacting OB/GYN Practice
Expanding the Conversation on Opioid-Induced Constipation
Volume II: Expanding Evidence for the Role of Rapid ART Initiation in HIV Practice
Improving Patient Outcomes Through Shared Clinical Decision Making
Mechanistic Insights and Evolving Treatment Options
Clinical Resource Center
A Case-Based Conversation on Managing Asthma and Chronic Rhinosinusitis With Nasal Polyposis
The Clinical and Utilization Benefits of Exacerbation Prevention
A PrEP Primer
A Foundation for Managed Care
Cardiovascular and Renal Outcomes With SGLT2 Inhibitors
Best Practices for Primary Care
New Paths to Chronic Pain Management
What the Pharmacist Needs to Know about PrEP
Unlocking Novel Paths to Patient Care
The Increasing Role of JAK Inhibitors
Preventing COPD Exacerbations to Improve Outcomes
A Whole Patient Case Series
Getting on the Fast Track to Identify AxSpA
Establishing Clinical Readiness Through Mentored Learning
Interdisciplinary Strategies for Adult and Pediatric Patients
Interdisciplinary Management of Eosinophilic Esophagitis and Hereditary Angioedema
Reducing LDL-C and a Lifetime of Cardiovascular Risk
Updates, Clinical Scenarios, and Future Directions
A Multidisciplinary Look at Early Diagnosis and Management
Best Practices for Diagnosis and Management
An Update on Best Practices
New Avenues to Pre-Exposure Prophylaxis
Are You Aware of New Blood-Based Multi-Cancer Screening Tools
A Look at the Changing HIV Playing Field
A “How To” Series Spanning Policy to Practice
Test Your Mastery!
Building Bridges to Reach People who Inject Drugs with the Goal of Employing PrEP for HIV Prevention
Bringing HIV Prevention to a New Level
Optimizing HIV Prevention in Primary Care
What You Need to Know About New Blood-Based Screening Tools
Monoclonal Antibodies for the Prevention and Treatment of COVID-19
Exploring New Treatment Avenues in Nonadvanced Systemic Mastocytosis
Practical Updates on the 2023 GOLD Guidelines
A Phone-a-Friend CME Series – Volume 2
Best Practices for Screening, Diagnosis, and Management
Incorporating New Data and Updated Guidelines Into Daily Practice
Focus on Psoriasis
Capitalizing on BCMA-Directed Therapies
From the Airway Epithelium to Improved Patient Outcomes
Exercising Best Practices for Hospitalized Patients
Accelerating Diagnosis and Treatment
