Targeting type 2 inflammation and epithelial alarmins in chronic obstructive pulmonary disease: a biologics outlook.
Rabe KF, et al. Am J Respir Crit Care Med. 2023;208(4):395-405.
Dupilumab for COPD with type 2 inflammation indicated by eosinophil counts.
Bhatt SP, et al. N Engl J Med. 2023;389(3):205-214.
Dupilumab for COPD with Blood Eosinophil Evidence of Type 2 Inflammation.
Bhatt SP, et al. N Engl J Med. 2024;390(24):2274-2283.
Mepolizumab for eosinophilic chronic obstructive pulmonary disease.
Pavord ID, et al. N Engl J Med. 2017;377(17):1613-1629.
Predicting response to benralizumab in chronic obstructive pulmonary disease: analyses of GALATHEA and TERRANOVA studies.
Criner GJ, et al. Lancet Respir Med. 2020;8(2):158-170.
The effect of exacerbation history on outcomes in the IMPACT trial.
Halpin DMG, et al. Eur Respir J. 2020;55(5):1901921.
An updated definition and severity classification of chronic obstructive pulmonary disease exacerbations: the Rome Proposal.
Celli BR, et al. Am J Respir Crit Care Med. 2021;204(11):1251-1258.
GUIDELINES
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease.
Global Initiative for Chronic Obstructive Lung Disease (GOLD). 2024 report.
CLINICAL PRACTICE TOOLS AND RESOURCES
The COPD Foundation Pocket Consultant Guide Mobile App
The COPD Pocket Guide, provided by the COPD Foundation, contains comprehensive management information as well as resource tools. It can be downloaded onto any mobile device.
Modified Medical Research Council (mMRC) Dyspnea Scale
The mMRC scale, provided by MDCalc, allows for the baseline stratification of dyspnea in COPD, as well as other respiratory diseases.
Clinical COPD Questionnaire score (CCQ) and mortality.
Sundh J, et al. Int J Chron Obstruct Pulmon Dis. 2012;7:833-42.
The CCQ measures health status and can be used to assess health-related quality of life.
COPD Assessment Test (CAT)
The CAT allows assessment of the global impact of COPD (cough, sputum, dyspnea, chest tightness) on patient health status.
COPD Action Plan
The COPD Action Plan, provided by the American Lung Association, is a tool that facilitates the prevention, timely identification, and early and appropriate treatment of COPD exacerbations.
ATS Telemedicine Information Series
The American Thoracic Society offers patients educational materials on telemedicine as well as answers to frequently asked questions surrounding this topic.
PATIENT RESOURCES AND ADVOCACY ORGANIZATIONS
The COPD Foundation Pocket Consultant Guide Patient-Focused Mobile App
The COPD Pocket Guide for Patients was designed to improve disease management and communication with a patient’s health care team. It includes patient resources such as inhaler and exercise videos as well as tools such as the wallet card and daily symptom tracker that help collect and share information with the health care team. It can be downloaded onto any mobile device.
American Lung Association
The American Lung Association is the leading organization working to save lives by improving lung health and preventing lung disease through education, advocacy, and research.
COPD Foundation
The COPD Foundation’s mission is to prevent and cure COPD and to improve the lives of all people affected by COPD.
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
GOLD partners with health care professionals and public health officials to raise awareness of COPD and to improve prevention and treatment of this lung disease for patients around the world.
National Jewish Health
National Jewish Health integrates the latest scientific discoveries with coordinated care for lung, heart, and immune diseases. Their Patient Education Program provides many free educational opportunities and support groups to assist patients and caregivers with managing illnesses and chronic conditions, such as COPD.
Chapter 1: T2 Inflammation and COPD
Hot Topics in COPD: From Disease Phenotypes to Targeted Therapies
Faculty: | Surya P. Bhatt, MD, MSPH |
Release: | 10/23/2024 |
Expiration: | 10/23/2025 |
Chapter 2: Biologic Therapies for COPD
Hot Topics in COPD: From Disease Phenotypes to Targeted Therapies
Faculty: | Surya P. Bhatt, MD, MSPH |
Release: | 10/30/2024 |
Expiration: | 10/30/2025 |