A Breath of Fresh Air in Pediatric Asthma
Shared Decision-making in the Era of Biologics
A Parent’s Testimonial
Shared Decision-making in Pediatric Asthma
Asthma.
Patel SJ, Teach SJ. Pediatr Rev. 2019;40(11):549-567.
Which child with asthma is a candidate for biological therapies?
Bush A. J Clin Med. 2020;9(4):1237.
Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program.
Fitzpatrick AM, et al. J Allergy Clin Immunol. 2011;127(2):382-389.
Omalizumab for the treatment of exacerbations in children with inadequately controlled allergic (IgE-mediated) asthma.
Lanier B, et al. J Allergy Clin Immunol. 2009;124(6):1210-1216.
Long-term safety and pharmacodynamics of mepolizumab in children with severe asthma with an eosinophilic phenotype.
Gupta A, et al. J Allergy Clin Immunol. 2019;144(5):1336-1342.e7.
Predictors of enhanced response with benralizumab for patients with severe asthma: pooled analysis of the SIROCCO and CALIMA studies.
FitzGerald JM, et al. Lancet Respir Med. 2018;6(1):51-64.
Dupilumab efficacy and safety in moderate-to-severe uncontrolled asthma.
Castro M, et al. N Engl J Med. 2018;378(26):2486-2496.
Dupilumab efficacy and safety in children with uncontrolled, moderate-to-severe asthma: the phase 3 VOYAGE study.
Bacharier LB, et al. ATS 2021. Abstract A1204.
Efficacy and safety of tezepelumab in adults and adolocesents with severe, uncontrolled asthma: results the phase 3 NAVIGATOR study.
Menzies-Gow A, et al J Allergy Clin Immunol.2021;147(2):AB249.
Handouts
Shared Decision-making Tool
Helping families understand biologic therapy for severe pediatric asthma
Clinical Practice Tools
Clinical tools to assess asthma control in children.
Dinakar C, et al. Pediatrics. 2017:139(1):e20163438.
Assessing Asthma Control and Adjusting Therapy in Children.
The National Asthma Education and Prevention Program Expert Panel Report provides a stepwise approach to the assessment of asthma control in children as well as in adolescents within their 2007 Full Report (Figures 12-15).
Assessing Asthma Control and Adjusting Therapy in Children
The National Asthma Education and Prevention Program Expert Panel Report provides a stepwise approach to the assessment of asthma control in children as well as in adolescents within their 2007 Full Report (Figures 12-15).
Childhood Asthma Control Test (C-ACT)
This questionnaire includes 4 pictorial items and 3 verbal items and is appropriate for helping to assess asthma control in children 4 to 11 years old. A score of <19 on the C-ACT suggests asthma that is uncontrolled.
Asthma Control Test (ACT)
This 5-item questionnaire helps evaluate asthma control in children aged 12 years or older. A score of <20 on the ACT suggests asthma that is uncontrolled.
Asthma Control Questionnaire (ACQ-6)
This 6-item questionnaire helps assess asthma control in children aged 6 to 16 years and has a recall window of 1 week. Scores range from 1 (totally controlled) to 6 (severely uncontrolled).
Juniper EF, et al. Eur Respir J. 2010;36(6):1410-1416
Test for Respiratory and Asthma Control in Kids (TRACK)
This 5-item questionnaire helps assess asthma control in children 0 to 5 years old. A score <80 is suggestive of asthma that is uncontrolled.
American Academy of Pediatrics (AAP) Asthma Action Plan aged 0 to 5 years
These asthma action plans have been developed for children aged 0 to 5 years
American Academy of Pediatrics (AAP) Asthma Action Plan ≥6 years
These asthma action plans have been developed for children ≥6 years.
Clinical Practice Guidelines
Global Strategy for Asthma Management and Prevention.
Global Initiative for Asthma, 2021.
Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline.
Holguin F, et al. Eur Respir J. 2020;55(1):1900588.
Patient Advocacy Organizations and Resources
American Academy of Pediatrics (AAP)
AAP’s healthychildren.org website is powered by pediatricians and is a trusted resource for parents of children with asthma and allergies. Resources include useful tips from pediatricians on mitigating triggers, evolving information on asthma therapies, patient education videos centered around the proper use of medication devices, and much more.
Asthma and Allergy Foundation of America (AAFA)
AAFA is dedicated to improving the quality of life for people with asthma and allergic diseases through education, advocacy, and research.
American College of Allergy, Asthma & Immunology (ACAAI)
The ACAAI fosters a culture of collaboration and congeniality in which members work toward the common goals of patient care, education, advocacy, and research.
American Lung Association
The American Lung Association is the leading organization working to save lives by improving lung health and preventing lung disease through education, advocacy, and research..
American Thoracic Society (ATS)
The mission of the ATS is to improve health worldwide by advancing research, clinical care, and public health in respiratory disease, critical illness, and sleep disorders.
Chest Foundation
The CHEST Foundation creates trusted patient education resources and disease awareness campaigns that empower patients to engage in better managing their health.
A Breath of Fresh Air in Pediatric Asthma
Shared Decision-making in the Era of Biologics
| Faculty: | Mario Castro, MD, MPH; Wanda Phipatanakul, MD, MS |
| Release: | 08/03/2021 |
| Expiration: | 08/03/2022 |
