Reducing Risks in Asthma
Mucus Plugs and Airway Obstruction
Airway-occluding mucus plugs and mortality in patients with chronic obstructive pulmonary disease.
Diaz AA, et al. JAMA. 2023;329(21):1832-1839.
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction.
Dunican EM, et al. J Clin Invest. 2018;128(3):997-1009.
Mucus plugs and emphysema in the pathophysiology of airflow obstruction and hypoxemia in smokers.
Dunican EM, et al. Am J Respir Crit Care Med. 2021;203(8):957-968.
All plugged up—noninvasive mucus score to assess airway dysfunction in asthma.
Georas SN. J Clin Invest. 2018;128(3):906-909.
CT mucus score and 129Xe MRI ventilation defects after 2.5 years’ anti-IL5Rα in eosinophilic asthma.
McIntosh MJ, et al. Chest. 2023;s0012-3692(23):00189-00197.
Normalisation of MRI ventilation heterogeneity in severe asthma by dupilumab.
Svenningsen S, et al. Thorax. 2019;74(11):1087-1088.
Clinical Practice Guidelines
Global Strategy for Asthma Management and Prevention.
Global Initiative for Asthma, 2021.
Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline.
Holguin F, et al. Eur Respir J. 2020;55(1):1900588.
Patient Advocacy Organizations and Resources
Asthma and Allergy Foundation of America (AAFA)
AAFA is dedicated to improving the quality of life for people with asthma and allergic diseases through education, advocacy, and research.
American College of Allergy, Asthma & Immunology (ACAAI)
The ACAAI fosters a culture of collaboration and congeniality in which members work toward the common goals of patient care, education, advocacy, and research.
American Lung Association
The American Lung Association is the leading organization working to save lives by improving lung health and preventing lung disease through education, advocacy, and research.
American Thoracic Society (ATS)
The mission of the ATS is to improve health worldwide by advancing research, clinical care, and public health in respiratory disease, critical illness, and sleep disorders.
CHEST Foundation
The CHEST Foundation creates trusted patient education resources and disease awareness campaigns that empower patients to engage in better managing their health.
Reducing Risks in Asthma
Mucus Plugs and Airway Obstruction
| Faculty: | Monica Kraft, MD; Steve N. Georas, MD |
| Release: | 07/14/2023 |
| Expiration: | 07/14/2024 |
