Trends in Infectious Diseases: Updates on Treatment & Prevention Strategies for HIV and HCV
Rapid Start ART — A New Model for HIV Care
RAPID ART: high virologic suppression rates with immediate ART initiation in a vulnerable urban clinic population.
Coffey S, et al. AIDS. 2018. [Epub ahead of print]
Antiretroviral therapy for the prevention of HIV-1 transmission.
Cohen MS, et al. N Engl J Med. 2016;375(9):830-839.
Prevention of HIV-1 infection with early antiretroviral therapy.
Cohen MS, et al. N Engl J Med. 2011;365(6):493-505.
A rapid entry program in the South: improving access to care and time to viral suppression.
Colasanti J, et al. 25th Conference on Retroviruses and Opportunistic Infections (CROI) 2018; March 4−7, 2018; Boston, MA. Poster 1109.
Continuous retention and viral suppression provide further insights into the HIV care continuum compared to the cross-sectional HIV care cascade.
Colasanti J, et al. Clin Infect Dis. 2016;62(5):648-654.
HIV viral load and transmissibility of HIV infection: undetectable equals untransmittable.
Eisinger RW, et al. JAMA. 2019;321(5):451-452.
Linkage and antiretroviral therapy within 72 hours at a federally qualified health center in New Orleans.
Halperin J, et al. AIDS Patient Care STDS. 2018;32(2):39-41.
Rapid HIV care cuts time to viral suppression in half.
Schoen J, Gallagher G. Healio Infect Dis News. 2018.
Initiation of antiretroviral therapy in early asymptomatic HIV infection.
INSIGHT START Study Group. N Engl J Med. 2015;373(9):795-807.
Same-day HIV testing with initiation of antiretroviral therapy versus standard care for persons living with HIV: a randomized unblinded trial.
Koenig SP, et al. PLoS Med. 2017;14(7):e1002357.
Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in Lesotho: the CASCADE randomized clinical trial.
Labhardt ND, et al. JAMA. 2018;319(11):1103-1112.
Association of implementation of a universal testing and treatment intervention with HIV diagnosis, receipt of antiretroviral therapy, and viral suppression in East Africa.
Petersen M, et al. JAMA. 2017;317(21):2196-2206.
The effect of same-day observed initiation of antiretroviral therapy on HIV viral load and treatment outcomes in a U.S. public health setting.
Pilcher CD, et al. J Acquir Immune Defic Syndr. 2017;74(1):44-51.
Initiating antiretroviral therapy for HIV at a patient’s first clinic visit: the RapIT randomized controlled trial.
Rosen S, et al. PLoS Med. 2016;13(5):e1002015.
Trends in the San Francisco human immunodeficiency virus epidemic in the "Getting to Zero" era.
Scheer S, et al. Clin Infect Dis. 2018;66(7):1027-1034.
A trial of early antiretrovirals and isoniazid preventive therapy in Africa.
TEMPRANO ANRS 12136 Study Group. N Engl J Med. 2015;373(9):808-822.
Pooled week 48 efficacy and baseline resistance: B/F/TAF in treatment-naïve patients.
White K, et al. CROI 2018. March 4−7, 2018; Boston, MA. Abstract 532.
Patient Resources
Centers for Disease Control and Prevention (CDC): HIV Basics
The CDC is a division within the US Department of Health and Human Services (DHHS), the principal agency for protecting the health of all Americans. This comprehensive site provides extensive links to topics across the HIV-care continuum, including PrEP.
Smartphone Pill-Reminder Apps (Free)
Mango Health — Medicine Reminder and Manager for iPhone
Mango Health for Android
Medisafe Pill Reminder and Alarm for iPhone
Clinical Practice Guidelines
Guidelines for Managing Advanced HIV Disease and Rapid Initiation of Antiretroviral Therapy.
World Health Organization, 2017.
Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living With HIV.
US Department of Health and Human Services, 2017 (last updated March 2019).
HIV Testing Guidelines.
Centers for Disease Control and Prevention (CDC), 2018.
Clinical Resources
90–90–90: An Ambitious Treatment Target to Help End the AIDS Epidemic.
Joint United Nations Programme on HIV/AIDS (UNAIDS), 2014.
AIDSVu.
Emory University Rollins School of Public Health, Gilead Sciences, Inc., and the Center for AIDS Research at Emory University (CFAF), 2018.
AtlasPlus Presentation Slides: HIV Diagnoses by County, 2014.
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.
Database of Antiretroviral Drug Interactions.
HIV InSite. University of California, San Francisco, 2018.
Harm Reduction Coalition.
Status of State Medicaid Expansion Decisions: Interactive Map.
Kaiser Family Foundation, 2019.
