Suggested Readings
Pembrolizumab plus lenvatinib as first-line therapy for advanced non-clear-cell renal cell carcinoma (KEYNOTE-B61): a single-arm, multicentre, phase 2 trial.
Albiges L, et al. Lancet Oncol. 2023;24(8):881-891.
Cabozantinib plus nivolumab in patients with non–clear cell renal cell carcinoma: updated results from a phase 2 trial.
Fitzgerald KN, et al. Eur Urol. 2024:86(2):90-94.
Results of a multicenter phase II study of atezolizumab and bevacizumab for patients with metastatic renal cell carcinoma with variant histology and/or sarcomatoid features.
McGregor BA, et al. J Clin Oncol. 2020;38(1):63-70.
A comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma: a randomised, open-label, phase 2 trial.
Pal SK, et al. Lancet. 2021;397(10275):695-703.
Cabozantinib in combination with atezolizumab for advanced renal cell carcinoma: results from the COSMIC-021 study.
Pal SK, et al. J Clin Oncol. 2021;39(33):3725-3736.
Phase II study investigating the safety and efficacy of savolitinib and durvalumab in metastatic papillary renal cancer (CALYPSO).
Suárez C, et al. J Clin Oncol. 2023;41(14):2493-2502.
First-line pembrolizumab plus lenvatinib for non–clear cell renal cell carcinomas (nccRCC): extended follow-up of the phase 2 KEYNOTE-B61 study.
Voss MH, et al. J Clin Oncol. 2024;42(4 suppl 2).
Linked Resources
Guidelines
NCCN Guidelines®: Kidney Cancer, version 1.2025
Motzer RJ, et al. J Natl Compr Canc Netw. 2024.
Clinician Resources
Kidney Cancer Association
National Kidney Foundation
Kidney Cancer Coalition
Related activities
Webcast
0.50 AMA PRA
Oncology News: nccRCC Edition
A Tailored Approach: Evidence-Based Management Strategies for Advanced/Metastatic ncc-RCC
Faculty: | Sumanta K. Pal, MD, FASCO; Wesley Yip, MD |
Release: | 08/28/2024 |
Expiration: | 08/28/2025 |