Multi-Cancer Early Detection
Incorporating Blood-Based Screening Tools into Primary Care Practice
Cell-free DNA analysis in current cancer clinical trials: a review.
Cisneros-Villanueva M, et al. Br J Cancer. 2022;126(3):391-400.
Projected reductions in absolute cancer–related deaths from diagnosing cancers before metastasis, 2006–2015.
Clarke CA, et al. Cancer Epidemiol Biomarkers Prev. 2020;29(5):895-902.
Circulating tumor DNA (ctDNA) as a pan-cancer screening test: is it finally on the horizon?
Duffy MJ, et al. Clin Chem Lab Med. 2021;59(8):1353-1361.
Multi-cancer early detection: the new frontier in cancer early detection.
Guerra CE, et al. Annu Rev Med. 2024;75:67-81.
New genomic technologies for multi-cancer early detection: rethinking the scope of cancer screening.
Hackshaw A, et al. Cancer Cell. 2022;40(2):109-113.
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA.
Liu MC, et al. Ann Oncol. 2020;31(6):745-759.
Multicancer screening: one size does not fit all.
Putcha G, et al. JCO Precis Oncol. 2021:574-576.
Modelled mortality benefits of multi-cancer early detection screening in England.
Sasieni P, et al. Br J Cancer. 2023;129(1):72-80.
Blood-based tests for multicancer early detection (PATHFINDER): a prospective cohort study.
Schrag D, et al. Lancet. 2023;402(10409):1251-1260.
Sensitivity, specificity, and predictive values: foundations, pliabilities, and pitfalls in research and practice.
Trevethan R. Front Public Health. 2017;5:307.
Additional CME Opportunities
Can You Compete in Early Cancer Detection?
An online CME webcast
Hot Topics in Blood-Based Cancer Screening
Key Information on Multi-Cancer Early Detection From 2023 Spring Oncology Meetings
TOP 10 Early Cancer Detection Queries
What You Need to Know About Blood-Based Screening in Primary Care
Multi-Cancer Early Detection in Primary Care
What You Need to Know About New Blood-Based Screening Tools
Guidelines
US Preventive Services Task Force. Published A and B Recommendations for Cancer.
US Preventive Services Task Force. Breast Cancer: Screening. Final Recommendation Statement.
April 30, 2024
US Preventive Services Task Force. Prostate Cancer: Screening. Final Recommendation Statement.
May 8, 2018
Multicancer Early Detection Consortium. White paper on Multicancer Early Detection (MCED) Screening Guidance: A Recommended Care Pathway for Clinical Use of MCED Tests.
June 27, 2023
Clinician Resources
Prevent Cancer Foundation
Multi-cancer early detection coverage and legislation.
Surveillance, Epidemiology, and End Results (SEER) *Explorer
An interactive website for SEER cancer statistics. Surveillance Research Program, National Cancer Institute, Division of Cancer Control and Population Sciences.
Galleri Test Website
Menlo Park, CA: Grail LLC.
Multi-Cancer Early Detection
Incorporating Blood-Based Screening Tools into Primary Care Practice
| Faculty: | Candace T. Westgate, DO, MPH, FACOG |
| Release: | 06/17/2024 |
| Expiration: | 06/17/2025 |
