Cell-free DNA analysis in current cancer clinical trials: a review.
Cisneros-Villanueva M, et al. Br J Cancer. 2022;126(3):391-400.
Projected reductions in absolute cancer–related deaths from diagnosing cancers before metastasis, 2006–2015.
Clarke CA, et al. Cancer Epidemiol Biomarkers Prev. 2020;29(5):895-902.
Circulating tumor DNA (ctDNA) as a pan-cancer screening test: is it finally on the horizon?
Duffy MJ, et al. Clin Chem Lab Med. 2021;59(8):1353-1361.
New genomic technologies for multi-cancer early detection: rethinking the scope of cancer screening.
Hackshaw A, et al. Cancer Cell. 2022;40(2):109-113.
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set.
Klein EA, et al. Ann Oncol. 2021;32(9):1167-1177.
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA.
Liu MC, et al. Ann Oncol. 2020;31(6):745-759.
The PATHFINDER Study: assessment of the implementation of an investigational multi-cancer early detection test into clinical practice.
Nadauld LD, et al. Cancers (Basel). 2021;13(14):3501.
Multicancer screening: one size does not fit all.
Putcha G, et al. JCO Precis Oncol. 2021:574-576.
Blood-based tests for multicancer early detection (PATHFINDER): a prospective cohort study.
Schrag D, et al. Lancet. 2023;402(10409):1251-1260.
Sensitivity, specificity, and predictive values: foundations, pliabilities, and pitfalls in research and practice.
Trevethan R. Front Public Health. 2017;5:307.
Modelled mortality benefits of multi-cancer early detection screening in England.
Sasieni P, et al. Br J Cancer. 2023;129(1):72-80.
Related Activities
Hot Topics in Blood-Based Cancer Screening
Key Information on Multi-Cancer Early Detection From 2023 Spring Oncology Meetings
TOP 10 Early Cancer Detection Queries
What You Need to Know About Blood-Based Screening in Primary Care
Multi-Cancer Early Detection in Primary Care
What You Need to Know About New Blood-Based Screening Tools
Takeaway Poster
Should You Consider Multi-Cancer Early Detection (MCED) Screening?
Conference Abstracts
Abstracts presented at the American Association for Cancer Research (AACR) 2023 Annual Meeting
Cancer Res. 2023;83(suppl 7).
Abstracts presented at the American Society of Clinical Oncology (ASCO) 2023 Annual Meeting
J Clin Oncol. 2023;41(suppl 16) and 2023;41(suppl 17).
Abstracts presented at the National Comprehensive Cancer Network (NCCN) 2023 Annual Conference
J Natl Compr Canc Netw. 2023;21(3.5).
Guidelines
US Preventive Services Task Force. Published A and B Recommendations for Cancer.
US Preventive Services Task Force. Breast Cancer: Screening. Draft Recommendations Statement. May 9, 2023
US Preventive Services Task Force. Prostate Cancer: Screening. Final Recommendation Summary. May 8, 2018
Multicancer Early Detection Consortium. White paper on Multicancer Early Detection (MCED) Screening Guidance: A Recommended Care Pathway for Clinical Use of MCED Tests. June 27, 2023
Clinician Resources
Prevent Cancer Foundation
Multi-cancer early detection coverage and legislation.
Surveillance, Epidemiology, and End Results (SEER) *Explorer
An interactive website for SEER cancer statistics. Surveillance Research Program, National Cancer Institute, Division of Cancer Control and Population Sciences.
Galleri Test Website
Menlo Park, CA: Grail LLC.
Can You Compete in Early Cancer Detection?
A CME Jeopardy Activity
Faculty: | Mylynda B. Massart, MD, PhD; Charles P. Vega, MD, FAAFP; Richard A. Whittington, MD |
Release: | 10/27/2023 |
Expiration: | 11/01/2023 |
Can You Compete In Early Cancer Detection?
Online Activity
Faculty: | Mylynda B. Massart, MD, PhD; Charles P. Vega, MD, FAAFP; Richard A. Whittington, MD |
Release: | 12/15/2023 |
Expiration: | 12/15/2024 |