New Avenues in Hypertension
Evolving Management of Uncontrolled and Resistant Disease
RAAS Dysregulation and New Treatment Targets in Hypertension
Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial.
Azizi M, Sanghvi K, Saxena M, et al Lancet. 2021;397(10293):2476-2486.
Baxdrostat for uncontrolled and resistant hypertension: rationale and design of the phase 3 clinical trials BaxHTN, BaxAsia, and Bax24.
Flack JM, Azizi M, Brown JM, et al. Hypertens Res. 2025;48(11):2911-2923.
The emerging role of aldosterone synthase inhibitors in overcoming renin-angiotensin-aldosterone system therapy limitations: a narrative review.
Patel SK, Teoh H, Saunthar A, et al. Card Fail Rev. 2025;11:e20.
Lorundrostat in participants with uncontrolled hypertension and treatment-resistant hypertension: the Launch-HTN randomized clinical trial.
Saxena M, Laffin L, Borghi C, et al; Launch-HTN Investigators. JAMA. 2025;334(5):409-418.
Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial.
Schlaich MP, Bellet M, Weber MA, et al. Lancet. 2022;400(10367):1927-1937.
Residual risk in cardiovascular and renal diseases and the potential role of aldosterone synthase inhibitors.
Umanath K, Dwyer JP, Mentz RJ. Front Cardiovasc Med. 2026;13:1845339.
Patient Resources
Resistant hypertension: high blood pressure that’s hard to treat.
American Heart Association.
Clinical Guidelines and Resources
2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the prevention, detection, evaluation and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
Jones DW, Ferdinand KC, Taler SJ, et al. Circulation. 2025;152(11):e114-e218.
Blood pressure targets in adults with hypertension: a clinical practice guideline from the AAFP.
Coles S, Fisher L, Lin KW, et al. Am Fam Physician. 2022;106(6):722A-722K.
Primary aldosteronism: an Endocrine Society clinical practice guideline.
Adler GK, Stowasser M, Correa RR, et al. J Clin Endocrinol Metab. 2025;110(9):2453-2495.
Target:BP™ Self-Measured BP Quick Start Guide
Target:BP™ offers tools and resources to obtain actionable data to diagnose hypertension and assess control of blood pressure (BP), initiate and intensify evidence-based treatment, and support patient adherence to treatment.
20
2026
New Avenues in Hypertension
Evolving Management of Uncontrolled and Resistant Disease
| Time: | 8:30 AM-10:00 AM CT |
| Venue: | AAFP FMX - Omni Nashville Hotel |
| Location: | Omni Nashville - Nashville, TN |
| Faculty: | John M. Flack, MD, MPH; Kausik Umanath, MD, MS, FACP, FASN; Karol Watson, MD, PhD |
20
2026
New Avenues in Hypertension
Evolving Management of Uncontrolled and Resistant Disease
| Time: | 8:30 AM-10:00 AM CT |
| Venue: | Online - Virtual Live Stream |
| Location: | Online - Virtual Live Stream |
| Faculty: | John M. Flack, MD, MPH; Kausik Umanath, MD, MS, FACP, FASN; Karol Watson, MD, PhD |
