Meeting slides
Interactive presentation

Pathophysiology Underlying the development of CRSwNP

Suggested Readings

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials.

Bachert C., et al. Lancet. 2019;394(10209):1638-1650.

The Unified Airway Hypothesis: Evidence From Specific Interventions With Anti-IL-5 Biologic Therapy

Bachert C., et al. J Allergy Clin Immunol Pract. 2023;11(9):2630-2641.

How to manage recurrences after surgery in CRSwNP patients in the biologic era: a narrative review.

De Corso E., et al. Acta Otorhinolaryngol Ital. 2023;43(suppl 1):S3-S13.

EPOS2020/EUFOREA expert opinion on defining disease states and therapeutic goals in CRSwNP.

Fokkens W.J., et al. Rhinology. 2024;62(3):287-298.

Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials.

Gevaert P., et al. J Allergy Clin Immunol. 2020;146(3):595-605.

Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNPASE): a randomised, double-blind, placebo-controlled, phase 3 trial.

Han J.K., et al. Lancet Respir Med. 2021;9(10):1141-1153.

Consensus criteria for chronic rhinosinusitis disease control: an international Delphi study.

Sedaghat A.R., et al. Rhinology. 2023;61(6):519-530.

Outcome measures for chronic rhinosinusitis with nasal polyps.

Sedaghat A.R., et al. Rhinology. 2024;62(34):1-37. 

Associations between inflammatory endotypes and clinical presentations in chronic rhinosinusitis.

Stevens W.W., et al. J Allergy Clin Immunol Pract. 2019;7(8):2812-2820.e3.

Patient Advocacy Organizations and Resources

Asthma and Allergy Foundation of America (AAFA)

AAFA is dedicated to improving the quality of life for people with asthma and allergic diseases through education, advocacy, and research.

American Academy of Allergy, Asthma, and Immunology (AAAAI)

The AAAAI is the leading membership organization of more than 7,100 allergists/immunologists and patients' trusted resource for allergies, asthma and immune deficiency disorders.

American College of Allergy, Asthma & Immunology (ACAAI)

The ACAAI fosters a culture of collaboration and congeniality in which members work toward the common goals of patient care, education, advocacy, and research.

American Lung Association

The American Lung Association is the leading organization working to save lives by improving lung health and preventing lung disease through education, advocacy, and research.


American Thoracic Society (ATS)

The mission of the ATS is to improve health worldwide by advancing research, clinical care, and public health in respiratory disease, critical illness, and sleep disorders.

Chest Foundation 

The CHEST Foundation creates trusted patient education resources and disease awareness campaigns that empower patients to engage in better managing their health.

Linked Resources

Clinical Practice Guidelines

Global Strategy for Asthma Management and Prevention.

Global Initiative for Asthma, 2023.

European Position Paper on Rhinosinusitis and Nasal Polyps 2020.

Fokkens W.J., et al. Rhinology. 2020;58(suppl S29):1-464.

Patient-Reported Outcomes Measure (PROM)

Sinonasal Outcome Test-22 (SNOT-22)

Related activities
Webcast 
1.50 AMA PRA

Epithelial Cytokines and Chronic Airway Diseases

A Closer Look at Chronic Rhinosinusitis With Nasal Polyps

Faculty: Kathleen M. Buchheit, MD; Joseph K. Han, MD, FARS, FAAOA; Flavia Hoyte, MD
Release: 03/01/2025
Expiration: 04/01/2026