Targeting Clear Horizons
Finding the Path in Chronic Rhinosinusitis with Nasal Polyps
Burden of disease in chronic rhinosinusitis with nasal polyps.
Bachert C, et al. J Asthma Allergy. 2021;14:127-134.
Phenotypes in chronic rhinosinusitis.
McCormick JP, et al. Curr Allergy Asthma Rep. 2020;20(7):20.
Biomarkers in chronic rhinosinusitis with nasal polyps.
Workman AD, et al. Immunol Allergy Clin North Am. 2018; 38(4):679-692.
Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials.
Bachert C, et al. Lancet. 2019;394(10209):1638-1650.
Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials.
Gevaert P, et al. J Allergy Clin Immunol. 2020;146(3):595-605.
EValuating trEatment RESponses of dupilumab versus omalizumab in Type 2 patients: the EVEREST Trial.
Gomez LDP, et al. J Allergy Clin Immunol. 2022;149(2): Abstract 145.
Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomized, double-blind, placebo-controlled, phase 3 trial.
Han JK, et al. Lancet Respir Med. 2021;9(10):1141-1153.
Mepolizumab induced loss of smell improvement in patients with chronic rhinosinusitis with nasal polyps from the SYNAPSE Study.
Mullo J, et al. J Allergy Clin Immunol. 2022;149(2): Abstract 481.
Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: a randomized, placebo-controlled trial.
Bachert C, et al. J Allergy Clin Immunol. 2021;149(4):1309-1317.e12.
Clinical Practice Guidelines and Position Papers
EUFOREA expert board meeting on uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) and biologics: definitions and management.
Bachert C, et al. J Allergy Clin Immunol. 2021;147(1):29-36.
Chronic rhinosinusitis with nasal polyps (CRSwNP) position paper, 2021.
Australasian Society of Clinical Immunology and Allergy (ASCIA).
European position paper on rhinosinusitis and nasal polyps, 2020.
Fokkens WJ, et al. Rhinology. 2020;58(suppl S29):1-464.
Clinical Practice Tools
Sino-Nasal Outcome Test (SNOT-22) Questionnaire
Sinus Control Test (SCT)
Questionnaire of Olfactory Disorders (QOD)
Patient Advocacy Organizations and Resources
Asthma and Allergy Foundation of America (AAFA)
AAFA is dedicated to improving the quality of life for people with asthma and allergic diseases including nasal polyps through education, advocacy, and research.
American Academy of Allergy, Asthma & Immunology (AAAAI)
AAAAI is dedicated to the advancement of the knowledge and practice of allergy, asthma, and immunology for optimal patient care.
Targeting Clear Horizons
Finding the Path in Chronic Rhinosinusitis with Nasal Polyps
| Faculty: | Joseph K Han, MD, FARS, FAAOA; Anju T. Peters, MD, MSCI |
| Release: | 04/29/2022 |
| Expiration: | 04/29/2023 |
