Updates on Chronic Rhinosinusitis With Nasal Polyps
Uncovering Epithelial Targets in the Upper Airways
Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials.
Bachert C, et al. Lancet. 2019;394(10209):1638-1650.
The unified airway hypothesis: evidence from specific interventions with anti-IL-5 biologic therapy.
Bachert C, et al. J Allergy Clin Immunol Pract. 2023;11(9):2630-2641.
How to manage recurrences after surgery in CRSwNP patients in the biologic era: a narrative review.
De Corso E, et al. Acta Otorhinolaryngol Ital. 2023;43(suppl 1):S3-S13.
EPOS2020/EUFOREA expert opinion on defining disease states and therapeutic goals in CRSwNP.
Fokkens WJ, et al. Rhinology. 2024;62(3):287-298.
Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials.
Gevaert P, et al. J Allergy Clin Immunol. 2020;146(3):595-605.
Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNPASE): a randomised, double-blind, placebo-controlled, phase 3 trial.
Han JK, et al. Lancet Respir Med. 2021;9(10):1141-1153.
Consensus criteria for chronic rhinosinusitis disease control: an international Delphi study.
Sedaghat AR, et al. Rhinology. 2023;61(6):519-530.
Associations between inflammatory endotypes and clinical presentations in chronic rhinosinusitis.
Stevens WW, et al. J Allergy Clin Immunol Pract. 2019;7(8):2812-2820.e3.
Clinical Practice Guidelines
Global Strategy for Asthma Management and Prevention.
Global Initiative for Asthma, 2023.
European Position Paper on Rhinosinusitis and Nasal Polyps 2020.
Fokkens WJ, et al. Rhinology. 2020;58(suppl S29):1-464.
Patient Advocacy Organizations and Resources
Asthma and Allergy Foundation of America (AAFA)
AAFA is dedicated to improving the quality of life for people with asthma and allergic diseases through education, advocacy, and research.
American College of Allergy, Asthma & Immunology (ACAAI)
The ACAAI fosters a culture of collaboration and congeniality in which members work toward the common goals of patient care, education, advocacy, and research.
American Lung Association
The American Lung Association is the leading organization working to save lives by improving lung health and preventing lung disease through education, advocacy, and research.
American Thoracic Society (ATS)
The mission of the ATS is to improve health worldwide by advancing research, clinical care, and public health in respiratory disease, critical illness, and sleep disorders.
Chest Foundation
The CHEST Foundation creates trusted patient education resources and disease awareness campaigns that empower patients to engage in better managing their health.
Updates on Chronic Rhinosinusitis With Nasal Polyps
Uncovering Epithelial Targets in the Upper Airways
| Faculty: | Tanya M. Laidlaw, MD; Joseph K. Han, MD; Flavia Hoyte, MD |
| Release: | 10/26/2024 |
| Expiration: | 11/23/2024 |
