Suggested Readings

The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2.

Cathcart AL, Havenar-Daughton C, Lempp FA, et al. bioRxiv. 2021. [Epub ahead of print]

Effect of bamlanivimab vs placebo on incidence of COVID-19 among residents and staff of skilled nursing and assisted living facilities: a randomized clinical trial.

Cohen MS, Nirula A, Mulligan MJ, et al. JAMA. 2021;326(1):46-55

Outcomes of laboratory-confirmed SARS-CoV-2 infection in the Omicron-driven fourth wave compared with previous waves in the Western Cape Province, South Africa.

Davies MA, Kassanjee R, Rosseau P, et al. medRxiv. 2022. [Epub ahead of print]

Evaluation of COVID-19 vaccine breakthrough infections among immunocompromised patients fully vaccinated with BNT162b2.

Di Fusco M, Moran MM, Cane A, et al. J Med Econ. 2021;24(1):1248-1260.

Safety and efficacy of combination SARS-CoV-2 monoclonal neutralizing antibodies BRII-196 and BRII-198 in non-hospitalized COVID-19 patients.

Evering T. IDWeek; September 29-October 3, 2021. Virtual conference.

At the heart of the matter: unmasking and addressing the toll of COVID-19 on diverse populations.

Haynes N, Cooper LA, Albert MA. Circulation. 2020;142(2):105-107.

PROVENT: Phase 3 study of efficacy and safety of AZD7442 (tixagevimab/cilgavimab) for pre-exposure prophylaxis of COVID-19 in adults. 

Levin M, et al. IDWeek; September 29-October 3, 2021. Virtual conference.

AZD7442 demonstrates prophylactic and therapeutic efficacy in non-human primates and extended half-life in humans.

Loo Y-M, McTamney PM, Arends RH, et al. medRxiv. 2021.08.30.21262666.

Subcutaneous REGEN-COV antibody combination to prevent Covid-19.

O’Brien MP, Forleo-Neto E, Musser BJ, et al. N Engl J Med. 2021. [Epub ahead of print].

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Clinical Updates

Recent Developments in Anti-SARS-CoV-2 Monoclonal Antibodies for Treatment and Prevention

Faculty: Onyema Ogbuagu, MBBCh, FACP, FIDSA
Release: 02/23/2022
Expiration: 02/23/2023