Mini Curriculum

Evolving Approaches to Alzheimer’s Disease

Finding the Way Forward

Suggested Readings

The future of anti-amyloid trials.

Aisen PS, Cummings J, Doody R, et al. J Prev Alzheimers Dis. 2020;7(3):146-151.

2021 Alzheimer’s disease facts and figures.

Alzheimer’s Association.

Neuropathological stageing of Alzheimer-related changes.

Braak H, Braak E. Acta Neuropathol. 1991;82(4):239-259.

EMERGE and ENGAGE topline results: two phase 3 studies to evaluate aducanumab in patients with early Alzheimer’s disease.

Budd Haeberlein S, von Hehn C, Tian Y, et al. Presented at: 12th Clinical Trials on Alzheimer’s Disease; December 4-7, 2019; San Diego, CA.

Magnetic resonance imaging in Alzheimer's disease and mild cognitive impairment.

Chandra A, Dervenoulas G, Politis M. J Neurol. 2019;266(6):1293-1302.

Biomarkers for Alzheimer's disease. Where we stand and where we are headed.

Chrem Méndez P, Surace E, Bérgamo Y, et al. Medicina (B Aires). 2019;79(Spec 6/1):546-551.

Imaging and molecular mechanisms of Alzheimer's disease: a review.

Femminella GD, Thayanandan T, Calsolaro V, et al. Int J Mol Sci. 2018;19(12):3702.

Costly new Alzheimer disease medications on the horizon—financing alternatives for Medicare.

Fleming WK, Brown CR, Shrank WH. JAMA Health Forum. 2020;1(9):e201148.

Pharmacotherapy of Alzheimer's disease: seeking clarity in a time of uncertainty.

Husna Ibrahim N, Yahaya MF, Mohamed W, et al. Front Pharmacol. 2020;11:261.

A/T/N: an unbiased descriptive classification scheme for Alzheimer disease biomarkers.

Jack CR Jr, Bennett DA, Blennow K, et al. Neurology. 2016;87(5):539-547.

The diagnosis and management of mild cognitive impairment: a clinical review.

Langa KM, Levine DA. JAMA. 2014;312(23):2551-2561.

Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older.

Larson EB, Wang L, Bowen JD, et al. Ann Intern Med. 2006;144(2):73-81.

Risk factors for predicting progression from mild cognitive impairment to Alzheimer's disease: a systematic review and meta-analysis of cohort studies.

Li JQ, Tan L, Wang HF, et al. J Neurol Neurosurg Psychiatry. 2016;87(5):476-484.

Donanemab in early Alzheimer's disease.

Mintun MA, Lo AC, Duggan Evans C, et al. N Engl J Med. 2021. Epub ahead of print.

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease.

Panza F, Lozupone M, Logroscino G, Imbimbo BP. Nat Rev Neurol. 2019;15(2):73-88.

Increasing precision of clinical diagnosis of Alzheimer's disease using a combined algorithm incorporating clinical and novel biomarker data.

Sabbagh MN, Lue LF, Fayard D, Shi J. Neurol Ther. 2017;6(suppl 1):83-95.

Persistence of BAN2401-mediated amyloid reductions post-treatment: a preliminary comparison of amyloid status between the core phase of BAN2401-G000-201 and baseline of the open-label extension phase in subjects with early Alzheimer’s disease.

Swanson C, Zhang Y, Dhadda S, et al. Neurology. 2020;94(suppl 15):1330.

Potential new approaches for diagnosis of Alzheimer’s disease and related dementias.

Turner RS, Stubbs T, Davies DA, Albensi BC. Front Neurol. 2020;11:496.

What are the difficulties of implementing innovative pharmacy practice models in the care of patients with dementia?

Wimo A. Expert Rev Pharmacoecon Outcomes Res. 2021;21(1):1-4.

Economic burden of Alzheimer disease and managed care considerations.

Wong W. Am J Manag Care. 2020;26(suppl 8):S177-S183.

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