Efficacy and safety of doravirine/islatravir in heavily treatment-experienced participants living with HIV-1: results from a randomized trial.
Carr A, Mngqibisa R, Khaertynova I, et al. AIDS. 2025;40(2):189-197.
Use of long-acting injectable cabotegravir/rilpivirine in people with HIV and adherence challenges.
Christopoulos KA, Hickey MD, Rana A. Curr Opin HIV AIDS. 2025;20(1):11-18.
Early experience implementing long-acting injectable cabotegravir/rilpivirine for human immunodeficiency virus-1 treatment at a Ryan White-funded clinic in the US South.
Collins LF, Corbin-Johnson D, Asrat M, et al. Open Forum Infect Dis. 2022;9(9):ofac455.
Phase 3 study of ibalizumab for multidrug-resistant HIV-1.
Emu B, Fessel J, Schrader S, et al. N Engl J Med. 2018;379(7):645-654.
Mechanisms of motivational interviewing for antiretroviral medication adherence in people with HIV.
Hogan A, Catley D, Goggin K, Evangeli M. AIDS Behav. 2020;24(10):2956-2965.
Mechanisms of motivational interviewing for antiretroviral medication adherence in people with HIV.
Hogan A, Catley D, Goggin K, et al. AIDS Behav. 2020;24(10):2956-2965.
Safety and efficacy of the HIV-1 attachment inhibitor prodrug fostemsavir in heavily treatment-experienced individuals: week 96 results of the phase 3 BRIGHTE study.
Lataillade M, Lalezari JP, Kozal M, et al. Lancet HIV. 2020;7(11):e740-e751.
Resistance analyses in heavily treatment-experienced people with HIV treated with the novel HIV capsid inhibitor lenacapavir after 2 years.
Margot NA, Jogiraju V, Pennetzdorfer N, et al. J Infect Dis. 2025;231(5):1239-1245.
Subcutaneous lenacapavir in people with multidrug-resistant HIV-1: 156 week results of the CAPELLA study.
Ogbuagu O, Wiznia A, McGowan JP, et al. Open Forum Infect Dis. 2025;13(1):ofaf763.
A randomized trial to compare dolutegravir plus boosted darunavir versus recommended standard of care antiretroviral regimens in people with HIV-1, whose first-line non-nucleoside reverse transcriptase inhibitor therapy has failed: final 96-week results of the D2EFT study.
Nyein PP, Borok M, Eriobu N, et al. Clin Infect Dis. 2026;81(6):e568-e580.
Efficacy and safety of dolutegravir or darunavir in combination with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection (NADIA): week 96 results from a prospective, multicentre, open-label, factorial, randomised, non-inferiority trial.
Paton NI, Musaazi J, Kityo C, et al. Lancet HIV. 2022;9(6):e381-e393.
Cabotegravir plus rilpivirine for persons with HIV and adherence challenges.
Rana AI, Zheng L, Castillo-Mancilla J, et al. N Engl J Med. 2026;394(9):858-871.
HIV viral suppression with use of long-acting antiretroviral therapy in people with and without initial viremia.
Spinelli MA, Heise MJ, Gistand N, et al. JAMA. 2025;333(16):1451-1453.
CLINICAL PRACTICE GUIDELINES
EACS guidelines
European AIDS Clinical Society
Antiretroviral drugs for treatment and prevention of HIV in adults: 2024 recommendations of the International Antiviral Society-USA Panel.
Gandhi RT, Landovitz RJ, Sax PE, et al. JAMA. 2024. [Epub ahead of print]
Guidelines for the use of antiretroviral agents in adults and adolescents living with HIV.
US Department of Health and Human Services
CLINICIAN RESOURCES
Clinical Guidelines Program: HIV Treatment
New York State Department of Health AIDS Institute
Clinician-to-Clinician Advice
National Clinician Consultation Center; University of California, San Francisco
HIV Drug Resistance Database.
Stanford University.
PATIENT AND CAREGIVER RESOURCES
Living With HIV
Centers for Disease Control and Prevention
Public HIV resources
National Institutes of Health
The HIV Journey
Mitigating Virologic Failure in HIV at Critical Clinical Crossroads
| Faculty: | Monica Gandhi, MD, MPH; Jürgen Rockstroh, MD |
| Release: | 07/20/2026 |
| Expiration: | 07/20/2027 |
